There's a lot of competition out there (there are about 700 contenders), but my picks would be:
1. Djinn&Tonic
2. nancydruid
3. Harcourt Fenton Mudd
4. united fruitcake outlet
5. Dr. Stupid
6. I_Am_Not_Mad
7. odulvai_thereafter
8. Fishgut Bob
9. Lulz Ron Hubbard
10. the_last_name_left
So say something, already!