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"I would rather deal with autism (even though some days I go bananas) than bury a child to a disease that could have been prevented."
It is patently obvious to me that Wakefield would not have had to falsify his data to indicate an association between severe ASD and GI disturbances. They are there.
The Seat of the Soul
The Origins of the Autism Epidemic
Biological Causes of Autism
These studies question a purely genetic etiology
* Singh VK, Rivas WH. Prevalence of serum antibodies to caudate nucleus in autistic children.
Neurosci Lett. 2004 Jan 23;355(1-2):53-6. PMID: 14729233
* Furlano RI, Anthony A, Day R, Brown A, McGarvey L, Thomson M, Forbes A, Wakefield AJ, Walker-Smith JA. Murch SH. Colonic CD8 and gamma delta T-cell infiltration with damage in children with autism.
J Paediatr 2001 Mar;138(3):366-72 PMID: 11241044
* Furlano RI, et al. Colonic CD8 and __ T-cell infiltration with epithelial damage in children with autism.
Journal of Pediatrics 2001 138:366-372.
* Horvath K and Perman JA, Autistic disorder and gastrointestinal disease,
Current Opinion in Pediatrics 2002;14:583 587 PMID: 12352252
* Horvath K and Perman JA, Autistic disorder and gastrointestinal symptoms
Curr Gastroenterol Rep. 2002 Jun;4(3):251-8. PMID: 12010627
* Torrente F, Ashwood P, Day R, Machado N, Furlano RI, Anthony A, Davies SE, Wakefield AJ, Thomson MA, Walker-Smith JA, Murch SH. Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism.
Mol Psychiatry. 2002;7(4):375-82, 334. PMID: 11986981
* Ashwood P, Anthony A, Pellicer AA, Torrente F, Walker-Smith JA, Wakefield AJ. Intestinal lymphocyte populations in children with regressive autism: evidence for extensive mucosal immunopathology.
J Clin Immunol. 2003 Nov;23(6):504-17. PMID: 15031638
* Ashwood P, Anthony A, Torrente F, Wakefield AJ. Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulatory interleukin-10.
J Clin Immunol. 2004 24(6):664-73. PMID: 15622451
* Torrente F, Anthony A, Heuschkel RB, Thomson MA, Ashwood P, Murch SH. Focal-enhanced gastritis in regressive autism with features distinct from Crohn's and Helicobacter pylori gastritis.
Am J Gastroenterol. 2004 Apr;99(4):598-605. PMID: 15089888
* Jyonouchi H, Geng L, Ruby A, Reddy C, Zimmerman-Bier B. Evaluation of an association between gastrointestinal symptoms and cytokine production against common dietary proteins in children with autism spectrum disorders.
J Pediatr. 2005 May;146(5):605-10. PMID: 15870662
* Jyonouchi H, Geng L, Ruby A, Zimmerman-Bier B. Dysregulated Innate Immune Responses in Young Children with Autism Spectrum Disorders: Their Relationship to Gastrointestinal Symptoms and Dietary Intervention.
Neuropsychobiology 2005 51(2):77-85. PMID: 15741748
* Carnegie Mellon
Brian Deer Shows True Colors, Blames Parents for Autism
Pow! By John Stone
A fundamental question in the latest controversy surrounding Brian Deer and Andrew Wakefield is how competent and objective a reporter is he? With so much hidden – the data for his latest article, his communications with the GMC – on what basis do we accept the objectivity of his world view? Is this someone with a balanced and lucid account of events? Has he any competence to interpret medical data, for which we only have his word. A still continuing discussion on the web blog LeftBrain/RightBrain has left him looking exposed – challenged to produce his GMC correspondence, the only potential defence he has that he did not unduly try to influence the prosecution of Andy Wakefield, he has become brittle. At one point he comments on the group of parents challenging him:
Brian Deer on February 16th, 2009 23:10:36
Well, actually Joseph, I didn’t intend that observation as an insult. I made it as a shorthand way of raising an issue that I believe may reasonably be raised.
I genuinely think that the three individuals I was criticising – and I know who all three of them are – do need to question whether their personal behavioural issues are indicative of a better explanation for their children’s issues. Certainly a lot better explanation than MMR.
The festering nastiness, the creepy repetitiveness, the weasly, deceitful, obsessiveness, all signal pathology to me.
ANOTHER AUTISM CASE WINS IN VACCINE COURT
By Robert F. Kennedy, Jr.
On February 12, the federal "Vaccine Court" in Washington issued a sweeping ruling in three highly touted "test cases" against families who claimed that their childrens' autism had been caused by vaccines. The Special Masters in those three cases found that Petitioners failed to establish causation between MMR vaccines, the mercury-laced vaccine preservative thimerosal, and autism (the court decision, which is under appeal, deferred any finding on a thimerosal-only theory of causation). The rulings could have a significant precedential impact on some 5,000 families who opted to bring their cases in the Omnibus Autism Proceedings (OAP) hoping that the vaccine court would officially hold that the MMR vaccine or thimerosal had caused autism in their children.
The New York Times joined the government Health Agency (HRSA) and its big pharma allies hailing the decisions as proof that the scientific doubts about vaccine safety had finally been "demolished." The US Department of Health and Human services said the rulings should "help reassure parents that vaccines do not cause autism." The Times, which has made itself a blind mouthpiece for HRSA and a leading defender of vaccine safety, joined crowing government and vaccine industry flacks applauding the decisions like giddy cheerleaders, rooting for the same court that many of these same voices viscously derided just one year ago, after Hannah Poling won compensation for her vaccine induced autism.
But last week, the parents of yet another child with autism spectrum disorder (ASD) were awarded a lump sum of more than $810,000 (plus an estimated $30-40,000 per year for autism services and care) in compensation by the Court, which ruled that the measels-mumps-rubella (MMR) vaccine had caused acute brain damage that led to his autism spectrum disorder.
The family of 10-year-old Bailey Banks won their case quietly and without fanfare in June of 2007, but the ruling has only now come to public attention. In the remarkably clear and eloquent decision, Special Master Richard Abell ruled that the Banks had successfully demonstrated that "the MMR vaccine at issue actually caused the conditions from which Bailey suffered and continues to suffer."
Bailey's diagnosis is Pervasive Developmental Disorder -- Not Otherwise Specified (PDD-NOS) which has been recognized as an autism spectrum disorder by CDC, HRSA and the other federal health agencies since at least the 1990s.
In his conclusion, Special Master Abell ruled that Petitioners had proven that the MMR had directly caused a brain inflammation illness called acute disseminated encephalomyelitis (ADEM) which, in turn, had caused the autism spectrum disorder PDD-NOS in the child:
The Court found that Bailey's ADEM was both caused-in-fact and proximately caused by his vaccination. It is well-understood that the vaccination at issue can cause ADEM, and the Court found, based upon a full reading and hearing of the pertinent facts in this case, that it did actually cause the ADEM. Furthermore, Bailey's ADEM was severe enough to cause lasting, residual damage, and retarded his developmental progress, which fits under the generalized heading of Pervasive Developmental Delay, or PDD [an autism spectrum disorder]. The Court found that Bailey would not have suffered this delay but for the administration of the MMR vaccine, and that this chain of causation was... a proximate sequence of cause and effect leading inexorably from vaccination to Pervasive Developmental Delay.
The Bailey decision is not an isolated ruling. We now know of at least two other successful ADEM cases argued in Vaccine Court. More significantly, an explosive investigation by CBS News has found that since 1988, the vaccine court has awarded money judgments, often in the millions of dollars, to thirteen hundred and twenty two families whose children suffered brain damage from vaccines. In many of these cases, the government paid out awards following a judicial finding that vaccine injury lead to the child's autism spectrum disorder. In each of these cases, the plaintiffs' attorneys made the same tactical decision made by Bailey Bank's lawyer, electing to opt out of the highly charged Omnibus Autism Proceedings and argue their autism cases in the regular vaccine court. In many other successful cases, attorneys elected to steer clear of the hot button autism issue altogether and seek recovery instead for the underlying brain damage that caused their client's autism.
Medical records associated with these proceedings clearly tell the tale. In perhaps hundreds of these cases, the children have all the classic symptoms of regressive autism; following vaccination a perfectly healthy child experiences high fever, seizures, and other illnesses, then gradually, over about three months, loses language, the ability to make eye contact, becomes "over-focused" and engages in stereotypical head banging and screaming and then suffers developmental delays characteristic of autism. Many of these children had received the autism diagnosis. Yet the radioactive word "autism" appears nowhere in the decision.
Brian Deer’s Boss Joins MMR Manufacturer Glaxo’s Board
Posted on February 25, 2009 by childhealthsafety
MMR vaccine manufacturer GlaxoSmithKline has appointed to its Board the head of News International James Murdoch. Murdoch is also boss of The Sunday Times, London, England publisher of stories by freelance journalist Brian Deer to discredit research into the link between MMR vaccine and autism in the US and UK [James Murdoch joins Glaxo board - Andrew Jack and Ben Fenton Financial Times 2 February 2009].
James Murdoch took up his appointment alongside Sir Crispin Davis the CEO of The Lancet medical journal’s owners. Sir Crispin is brother of Judge Nigel Davis whose English High Court judgement in February 2004 saw the end of British children’s MMR vaccine injury claims [MMR Judge Faces Probe Over Brother's Links to Vaccine Firm - Evening Standard, London 9 May 2007].
The outcome of an investigation by the Office for Judicial Complaints found no impropriety and resulted in no action taken regarding the relationship between Judge Davis and his brother Crispin Davis’ GlaxoSmithKline board position. A statement issued on Judge Davis’ behalf to The Telegraph newspaper legal correspondent, Joshua Rosenberg stated that “the possibility of any conflict of interest had not occurred to him“. Sir Crispin Davis received a knighthood in June 2004.
Recent statements by UK Sunday Times’ journalist Brian Deer shows he helped the US Department of Justice present the US Court of Federal Claims on a number of occasions with last minute documents to defeat the prospects for the US children’s claims [Full quote below]. The production of last-minute evidence is a litigation tactic which can prejudice the Court’s view and can leave an opponent with little time to counter it. The Federal Court has previously upheld claims of US children developing autistic symptoms from vaccines including the MMR vaccine: [AUTISM - US Court Decisions and Other Recent Developments - It’s Not Just MMR]
A key potential rebuttal witness, Dr Andrew Wakefield could not come forward because of the journalist’s long-running personal campaign to discredit research into the link between the MMR vaccine and autism. The prospects for the US children were also already harmed by the journalist’s now seemingly inadequately researched reports published internationally since 2003 in the UK Sunday Times which have hindered research and are believed to have had a deterrent effect on other experts coming forward.
1963 - the BBC created 'Dr. Who' for a vaccine program tie-in.
Hence the police phone box prop.
WHO = World Health Organization, a hot topic of the Cold War.
Dr. Andrew Wakefield - the British physician who was accused in February by the Sunday Times of London of altering data in a 1998 paper on autistic children, bowel disease and the MMR vaccine - has filed a formal complaint against the freelance journalist who wrote the article.
Wakefield this week delivered the complaint against the journalist, Brian Deer, to the UK's Press Complaints Commission (PCC) - an independent body that investigates alleged inaccuracies, invasion of privacy and misreporting by the media.
The complaint accuses Deer of "publishing incorrect information and also of having a conflict of interest caused by his involvement in the General Medical Committee's (GMC) investigation of Wakefield," according to a news release issued by the doctor's advisors.
Wakefield - who now lives in Austin, TX - and two colleagues are currently the subject of hearings at the GMC, which has accused them of serious misconduct in the research and writing of the 1998 paper on autism and MMR vaccine.
"Mr. Deer has failed miserably as a reporter and has done great harm to me and many others conducting autism research," Wakefield said in the release.
The most sensational accusation against him printed in the Sunday Times held that Wakefield had altered and manipulated data on many of the 12 children who were written up in the paper.
Deer wrote: "The doctor who sparked the scare over the safety of the MMR vaccine for children changed and misreported results in his research, creating the appearance of a possible link with autism, a Sunday Times investigation has found."
Deer also said that, "Confidential medical documents and interviews with witnesses have established that Andrew Wakefield manipulated patients' data, which triggered fears that the MMR triple vaccine to protect against measles, mumps and rubella was linked to the condition."
The accusations made worldwide headlines and further lacerated Wakefield's already tarnished reputation within mainstream health and science circles. But Wakefield, in his 58-page complaint to the Press Commission, is finally pushing back.
"There is no basis in fact for any suggestion that I "manipulated patients' data" at any time," he says in the complaint. "There was no misreporting or changing of results by me," he wrote. "None of the evidence presented during the GMC hearing over the past year-and-a-half, supports any allegation of manipulation of data by either myself or any of the other 12 co-authors on the paper.
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