Coronavirus Crisis: Main Thread

[stickdog99]

[stickdog99]

JC on a Bike Interview: Gain of Function or Gain of Purity

[stickdog99]

[Mask]

Living In A World Without Sin Is Fatal

I’ve actually been meaning to write this post for about a year. The World Without Sin is the cinematic allusion that keeps on giving. Briefly put, it’s a phrase I lifted from the film Serenity that I use to refer to the creation of a clean and perfect (and thus false) world created by a blend of media and official opinion.

It is the end result of progressive capitalist propaganda. You can move into it, have the correct opinions, vote for the correct candidate, and -as long as you don’t look too closely- think of yourself as a good person operating in a benign world that you mostly understand. It is a place free of confusion or dissent, and The West Wing plays continuously on every screen. (The point of the film was that it took a tremendous amount of state violence, brutality and tyranny behind the scenes to create and maintain the world without sin, which is why I use the term.) A good example of this would be Sam Block’s tremendous hypocrisy in apparently being part of ATR/Caribbean/Latin religion while proudly working for the organisation -the US federal government- almost singularly responsible for Latin America’s suboptimal economic condition and living situation thanks to its sixty year campaign of coups, assassinations, rigged elections, drug dealing and gun running. (This is a perfect poster of American privilege.)

What made me want to write this post a year ago was the Canadian trucker strike. Nothing could be more ‘world without sin’ than the official media completely ignoring a convoy descending on the capital that was so large you could see it from space. Here was something you could see from space but you could not see in the official media. In the world of Canadian state television, there was no convoy. In reality, there was.

And this is the point of today’s post:

You can live in reality and hopefully not die.
Or you can live in the world without sin and you will.

Because it is now illegal for an Australian doctor to be honest with his or her patients about such topics as mRNA injections, this family anecdote will be non-specific. A female family member who has been having heart troubles since her second injection was told by her cardiologist that her troubles absolutely were caused by the injections -and he has many patients in the same situation- but if he said so publicly or officially he would lose his job.

World without sin and reality. Right there.

I didn’t end up writing the post about the truckers because more and more examples kept piling up and the post got too long and then it was this year and now it’s now. Now it’s a slightly different post.

For the past forty years, the people running the world have gotten away with running reality by fiat declaration. This accelerated from about the Obama era where a politician can just declare the economy is going great or that healthcare has dramatically improved and the reality of economic or medical hardship didn’t impinge on the world without sin. This method of reality creation by fiat declaration is not just going away, it is collapsing. The collapse is accelerating because the people running the world -long out of practice when it comes to dealing with reality- only know how to ‘declare’ it. So they’ll do more, they’ll accelerate censorship and crush dissent and it will be this process that finally brings it all down.

The good news is most people are already living in reality. That has been the point of my last couple of posts. Very few people still live in official reality/the world without sin.

Continued @ https://runesoup.com/2022/11/living-in-a-world-without-sin-is-fatal/

[stickdog99]

Excess UK death categories from 11 June and 19 August:

[stickdog99]

Excess mortality among 0-14 year-olds in Europe:

[stickdog99]

[stickdog99]

Ratio of COVID-19 deaths to COVID-19 cases in UK sequenced with first dose administration rates

[stickdog99]

Excess 2021 and 2020 Deaths in the Philippines compared to 2019. Highly positive excess deaths in the vaccine eligible compared to negative excess deaths in the vaccine ineligible.

[stickdog99]

Latest Walgreens Data: Uninjected Now LESS Likely to Test Positive Than Those Injected Within 3 Months. Those injected more than 3 months ago are 50% MORE likely to test positive for COVID. The uninjected account for 29% of Walgreens population & 24% of COVID tests, but just 17.6% of positive tests.



Pandemic of the Vaccinated. See Page 3

From page 5:

"Recent data shows that vaccinated patients make up 71% of our testing population."

On page 3, "Proportion of Tests", we see that this 71% of of the population now accounts for 82.4% (100% - 17.6% unvaccinated) of the COVID-19 positive tests at Walgreens.

[Belligerent Savant]

@Robber_Baron_
·
For every smug progressive who used Covid to push a social agenda & change election laws, thousands of children around the world suffered & died from poverty, abuse, neglect, hunger, & disease made worse by lockdowns.

It's absolutely appalling.

https://twitter.com/Robber_Baron_/statu ... 6oZ0yXFwdw

@Keggs719
·
States aren't even done counting votes & student loan forgiveness isn't happening anymore, masks suddenly work, and the pandemic actually ISN'T over since the "emergency" is extended.

I would laugh at your stupidity if it didn't affect my life as well.

https://twitter.com/Keggs719/status/159 ... 6oZ0yXFwdw

@kellytx2

But Joe recently said in an interview that Covid was over.

Joe Biden plans to extend COVID health emergency to April 2023: reports

https://twitter.com/kellytx2/status/159 ... 6oZ0yXFwdw

@legler_aaron
·
Replying to @TheEliKlein @NEJM and @nytimes

It is very sad to see NEJM essentially dissolve into a propaganda machine. Along with the
@CDCMMWR - both publications once highly respected now absolutely compromised.

https://twitter.com/legler_aaron/status ... 6oZ0yXFwdw

@TheEliKlein

The study published by the @NEJM & promoted by the @nytimes claiming masks in schools work well is thoroughly debunked, so must be retracted. The anonymous peer reviewers should face academic probation. The NY & Boston health commissioners who co-authored it gotta be disciplined.

https://twitter.com/TheEliKlein/status/ ... 6oZ0yXFwdw

@galexybrane
·
The Biden administration has decided to extend the covid-19 “emergency” until at least April. It’s not a coincidence that this was announced just 3 days after midterms. Extending the emergency has major implications for vaccine authorizations and ongoing mandates.

https://twitter.com/galexybrane/status/ ... 6oZ0yXFwdw

@DanielHadas2
·
I'm going to keep at this.

If there was no widespread social consent to lockdowns etc, why is this STILL happening, why has every politician and official who enabled this not been hounded out office?

@doc_gero

As a geriatrician, I want to remind you that for many / most nursing homes, they live (still) like it’s virtually March 2020 - although at least the prison-like window visits are gone. We’re all still masked.

Visits tightly regimented. “Quarantine” lockdowns of the facility for positive cases still recurrent. Plexiglass, social distancing signs, clean pen / dirty pen nonsense everywhere.

Communal dining (at least for all the nursing homes in our region) still banned.

For our residents it’s a grim, dismal, & depressogenic Groundhog Day they don’t seem to have any way out of.

Don’t forget them.

https://twitter.com/DanielHadas2/status ... 6oZ0yXFwdw

Lucy McBride, MD
@drlucymcbride

IMHO the very first class in medical school should be "Interpreting Scientific Literature: Confounders, Covariates & Lessons from Covid"

9:30 PM · Nov 10, 2022
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Anonymous epidemiologist
@Epi_An
·
Replying to @drlucymcbride

Yes, yes and yes! Also difference between observational studies and and RCTs. Too many MDs recently seem to forget (maybe ignore ?) these basics of epidemiology.


@eremeticus
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Replying to @drlucymcbride

Excellent idea, but perhaps a session on “Understanding the Sources of Your Data” should come first. Poor quality data is the bane of us statisticians…


@Mr_MonkeyDude
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Replying to @drlucymcbride

2nd. First should be, "respect your patients and their right to self-determination."

@facts1st2020
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Replying to @drlucymcbride

The garbage study from NEJM on school masking can be thrown into the lesson.

https://twitter.com/drlucymcbride/statu ... 6oZ0yXFwdw

Tracy Høeg, MD, PhD
@TracyBethHoeg

Unreal to me @NEJM published this study on masking I just talked to a @nytimes reporter re why it's clear there's at least 1 confounder

The blue line districts that lifted masking (at times 1, 2 & 3) had case counts that increased independent of when mask mandates were lifted!

https://twitter.com/TracyBethHoeg/statu ... 6oZ0yXFwdw

Kelley K
@KelleyKga

1/ Literally a day after the election, public health goes all in on masking kids again, this time with a widely criticized observational study by @EpiEllie. My comment from the pre-print still holds true:

Districts that unmasked are fundamentally different from ones that didn't.

The authors can do all the sensitivity analyses and adjustments they want, but there is just no way to account for all of the differences between these two groups - testing rates, natural immunity, vaccination, behavior outside school, family exposure, etc...

There are a lot of other specific technical criticisms people have pointed out, but the crux of it to me is just that masks are hardly the only important difference between these groups. This is the same issue that affects every observational mask study PH touts as evidence.

Also this...

Replying to @jonlevyBU @NEJM and 3 others

"The authors found that COVID-19 rates were similar among districts before the mask requirement was rescinded..." Does this look "similar"?!? I wonder why they started this graph when they did...

https://twitter.com/KelleyKga/status/15 ... 6oZ0yXFwdw

[Belligerent Savant]

Dr. Polar Bear, Ph. D
@PunditPandemic

A play in three acts:

https://twitter.com/PunditPandemic/stat ... RorqeRZ2fw

Michael Absoud
@MAbsoud

If you don’t like the answers, delete the tweet— is that how it works?

https://twitter.com/MAbsoud/status/1591 ... RorqeRZ2fw

Daniela
@daniela127
.
@medpagetoday deleted the poll, but not before 97% of 16,000 people said No to mandatory school masks.

https://twitter.com/daniela127/status/1 ... RorqeRZ2fw


Do you all see it yet, just how vile and despicable these people (anyone actively involved in these nudging/blatant propaganda tactics) are?

[Belligerent Savant]

And then there's the shots [and related mandates/coercion] -- an even more egregious affront to our collective human rights and well-being.

A number of you, again, continue to be blind to the full extent of the vile acts currently being perpetrated.

A number of you will direct your anger at me, and those like me, rather than perform a sober assessment of where we are, currently, and the blatant attempts to sow discord and chaos.

@EthicalSkeptic

So I guess my 7:1 estimation for the < 3 months vaxxed did not turn out so wrong after all...

What are the pharma trolls batting now? .000 ???

Not only were they wrong, they misled persons to their harm as well.





...

@db11770382

Replying to @EthicalSkeptic

AU govt update Nov 9, 2022:

"Pericarditis and myocarditis after COVID-19 vaccines ... * do occur in both females and males, at *any age*, and *after any dose*, including a third or fourth dose *

https://health.gov.au/resources/publica ... 9-vaccines



...

@gtown615
·
Replying to @db11770382, @Anvesaka88 and @EthicalSkeptic

The heart burns fat rather than glucose which has unstable blood levels.

Best theory I've heard is that in people with lower body fat the heart is more likely to absorb the Lipid Nanoparticles from the vaxes.

...

@Polymath300
·
Replying to @EthicalSkeptic

So RSV is a symptom of mRNA vaccine, is what I saw earlier

...

@infobot13
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Replying to @Polymath300 and @EthicalSkeptic

1. Many viral infections are more likely after mRNA vax; RSV, varicella, herpes, COVID etc. T cell immunity is degraded.
2 Variants have already escaped the bivalent vax
3. Heart muscle injury occurs in 3% of vaccinated
3. Since Omicron variant, the unvaccinated don’t die

https://twitter.com/EthicalSkeptic/stat ... Q6k6YLagdg

The above comments will have varying degrees of corroboration given how data is currently obfuscated, cherry-picked, subject to bias and confounding factors. These potential shortcomings are applicable to anyone.

But at this point it should be clear that what's happening is far worse than even many cynics anticipated a year ago.

But wait. Wait another 6 months. Wait another year. If there is a silver lining, it's that the worse it gets, the more people become aware. Even in this era of perpetual nudging, conditioning, and pervasive media mgmt of information.

Unfortunately it'll happen much later than it should.

[stickdog99]

https://www.cell.com/iscience/fulltext/S2589-0042(22)01816-8

Cell (scientific journal): "Striking changes were observed in the CD34+ cell (STEM CELL marker) fraction--the total numbers of CD34+ cells DRASTICALLY REDUCED 4-fold in the vaccinated donor group, in which this change was correlated to the induction of apoptosis in CD34+ cells."

Highlights

SARS-CoV-2 infection/vaccination correlate to the in vivo fate of CD34+ HSPCs (hematopoietic stem progenitor cells).
SARS-CoV-2 infection/vaccination correlate to hematopoiesis of CD34+ HSPCs.
SARS-CoV-2 vaccination correlates with CD34+ HSPC numbers/frequencies in the UCB.
Summary

Umbilical cord blood (UCB) is an irreplaceable source for hematopoietic stem progenitor cells (HSPCs). However, the effects of SARS-CoV-2 infection and COVID-19 vaccination on UCB phenotype, specifically the HSPCs therein, are currently unknown. We thus evaluated any effects of SARS-CoV-2 infection and/or COVID-19 vaccination from the mother on the fate and functionalities of HSPCs in the UCB. The numbers and frequencies of HSPCs in the UCB decreased significantly in donors with previous SARS-CoV-2 infection and more so with COVID-19 vaccination via the induction of apoptosis, likely mediated by IFN-γ-dependent pathways. Two independent hematopoiesis assays, a colony forming unit assay and a mouse humanization assay, revealed skewed hematopoiesis of HSPCs obtained from donors delivered from mothers with SARS-CoV-2 infection history. These results indicate that SARS-CoV-2 infection and COVID-19 vaccination impair the functionalities and survivability of HSPCs in the UCB, which would make unprecedented concerns on the future of HSPC-based therapies.

Full Text

Analysis of this paper

To assess the recovery time needed for decreased CD34+ cell numbers of donors following the vaccination/infection to baseline as established by the negative donor group, the % frequencies and numbers of CD34+ cells per 1 mL of UCB against the days post and vaccination were plotted. Both parameters were inversely correlated to the term following the vaccination, though there was no significance difference by the positivity for IgGs against SARS-CoV-2 S and N proteins, indicating that these impacts on CD34+ cells were largely caused by the vaccination, in which the trends continued without recovering to baseline over the entire gestation period.

Read this section as much as needed until it dawns upon you. The effects of decreasing CD34+ cell numbers were more pronounced among vaccinated rather than by infection status, meaning the stark differences in the reduction effect are caused by the vaccination. This is a solid argument for the HSCs paper I covered months ago, in which they demonstrate the negative effect the Spike Protein has on Stem Cells, and bring to the attention that perhaps the vaccines using Spike Protein could damage these cells too.

Following this the authors explain they did not find detectable levels of both N antigens or free S proteins, indicating that these changes were not derived from viral S of vaccine Spike, but these cells were becoming apoptotic (dying). Furthermore, there were no differences in cytokines in the plasma from Umbilical Cord, but one of their tests suggested the involvement of Interferon-Gamma, an old acquaintance around here.

Taken together, these data suggest that the IFN-γ-related signaling pathways promoted by SARS-CoV-2 infection could involve in the induction of apoptosis observed in CD34+ HSPCs and thus might affect the fate and survivability of CD34+ HSPC populations in the UCB.

A point of pride very early on, in the mRNA vaccine implementation was its (skewed) immune response and its broad, potent Interferon-Gamma response, a remarkable response “insert sales pitch here”. The pathway argued by the authors, which has precedence and evidence in literature is even more present among the vaccinated mothers, more pronounced after the second dose of the vaccine, and it lasted the entire gestation period.

While out of the scope of this paper, and not argued by the authors, this goes merely beyond creating a shortage of HSPCs for research, treatment, and possible new onset of hematological issues in HSP cells recipients, this clearly has the signs of premature aging of the immune system, the so-called “inflammaging”. A hallmark of this state in old people is the skewed immune system, and among many other aspects, a higher level and presence of Interferon-Gamma.

In the scope of the study alone, this already put to rest the “vaccination in gestating mothers is protective/harmless”, but I will go beyond it. From https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715736/

Collectively, these data suggest that both IFN-α and IFN-γ directly stimulate HSC proliferation, and, if the exposure is prolonged, result in a loss of repopulating activity. IFN signaling also appears to play a negative role in regulating HSC quiescence and repopulating activity under basal conditions. Of note, there is evidence (at least for IFN-γ) that IFN signaling regulates HSC function in humans. Specifically, Yang and colleagues showed that treatment of CD34+ CD38− human cord blood cells with IFN-γ markedly inhibits their ability to support multi-lineage hematopoiesis when transplanted into NOD-SCID mice.

I could keep citing literature, but for simplicity and time's sake I will finish the Gamma section here, the effects of chronic infection are extensive, and chronic stimulation of Interferon Gamma leads to a whole host of immunological changes, I would like to remember that this Interferon also modulates the presence of IDO, the enzymes that break down Tryptophan, and is a major player in the Kynurenine Pathway. Interferon Gamma also played a central role in a recent paper talking about Thymic atrophy in regard to SARS-CoV-2 infection.

And since the SARS-CoV-2 Spike as an Endotoxin Delivery me and two other friends have looked extensively down this route, because it is as clear as day that this play a major role in almost every single facet of this whole mess, either by canonical or non-canonical pathways. If the Spike Protein is Frankenstein, the capacity to modulate Endotoxins and biofilms are the body parts that constitute the monster.

...

Given everything I have written in this Substack, it is objectively true, and factual that the viral infection to a lower degree, the vaccination to an unparalleled degree has brought drastic changes to a third of the global population, and while I regard myself a competent complexity “guy”, we just can’t fathom the immunological shifts and evolutionary changes on pathogens this will set off.

We are in uncharted territory, and have been for a while now.

[stickdog99]

Fertility declines near the end of the COVID-19 pandemic: Evidence of the 2022 birth declines in Germany and Sweden