rigorousintuition.ca

Posted: **Thu Feb 03, 2022 1:20 pm**

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https://threadreaderapp.com/thread/1489 ... 53002.html

This FDA paper from July 2020 makes some very interesting points about mRNA vaccines:
Regulatory Considerations on the Development of mRNA Vaccines.
https://europepmc.org/article/med/32638114

"Replacing rare codons with those used more frequently does not always produce the desired effects"

"For example if translation is too rapid, the protein might not fold correctly into a functional antigen, and this can have the undesired consequences of reducing vaccine efficacy"

"The other modification required for production of a stable mRNA is the addition of the poly(A) tail. The length of the poly(A) tail can affect the translation efficiency, and thus, the expression level of the protein, and therefore, needs to be considered"

"Several mRNA versions of the antigen gene may need to be evaluated in preclinical toxicology and immunogenicity studies."

"If the LNPs contain a lipid component that is not a natural chemical but instead is a novel compound that has not been a part of another drug used in humans, it may need to be tested for toxicity, particularly as some cationic lipids have been found to be toxic in vivo"

"A toxicology study of a mRNA vaccine would generally include an assessment of the reactogenicity of the vaccine in a relevant animal model. However, because the mouse and human immune systems are not always concordant the assessment of potential reactogenicity can be complicated"

"A lipid-based particle encapsulating the mRNA might facilitate passage to distant organs and result in longer retention times. For this reason, biodistribution and retention studies have been requested for mRNA vaccines."

Posted: **Thu Feb 03, 2022 1:22 pm**

Joe Hillshoist » Wed Feb 02, 2022 11:31 pm wrote:
stickdog99 » 03 Feb 2022 13:25 wrote:

Among those under 80 years old, that 64 deaths from/with COVID-19 among the vaccinated compared to just 11 among the unvaccinated.

source: https://www.health.nsw.gov.au/Infectiou ... 220201.pdf
Do you know anything about maths?

What about the number of the population with vaccinations?

Exactly.

The vertical axis on the graphs is the absolute number not the % of those vaccinated.

There are far more individuals with two plus doses versus less doses; hence the absolute number of cases is more for the two doses but far less a percentage than those with less than two doses.

StickDog posts multitudes of items but does not exhibit the basic math skills to understand what they post, forget about statistics.

But as far as statistics, the numbers posted by authorities are often confusing and have errors. The county where I live posts a spreadsheet each business day and there are errors in the formulas but evidently no one really looks that close anyway. We need far less numbers but need numbers that make some sense.

Think we see politicians and some scientists make public statements or published stuff wanting to be optimistic for the public (pols), slanted toward their bias, or wanting to get attention from being among the first to be "correct". This adds to the confusion.

Have repeatedly said that the confusion and chaos looks deliberate with nasty goals in mind regarding most of us.

StickDog feeds their own confusion and seeds it through RI.

Posted: **Thu Feb 03, 2022 1:30 pm**

stickdog99 » Wed Feb 02, 2022 2:33 am wrote:
PufPuf93 » 02 Feb 2022 00:52 wrote:
stickdog99 » Tue Feb 01, 2022 4:54 pm wrote:How is it that pointing the finger at Russia or calling the trucker convoy a totally fringe movement is somehow supposed to allow one to continue supporting vaccine mandates for an omicron variant that we all know and agree said vaccines don't protect against?

Can anyone explain that to me?
Think maybe you should ask some of the medical students that you teach.
I think you should ask yourself.

Were I to ask my students this obvious question, some of them would undoubtedly report me to the administration, and I would then be summarily fired from my job. To a hearty round of applause from you for daring to ask?

Was ribbing you. Wish you no harm ever.

I do have a hard time imagining you teaching medical students in the Bay Area unless perhaps some type of alternative medicine. Medical students need to be reasonably intelligent and have a grasp of math and science. You do not appear to have the math nor science background and skills to teach medical students.

Posted: **Thu Feb 03, 2022 2:53 pm**

Belligerent Savant » Tue Feb 01, 2022 9:33 pm wrote:.
Probably one of the most accurate and succinct takes on covid:

If only we could have seen the pandemic as something to be endured, survived, mitigated – rather than controlled or ended through our interventions – then we could have been in a much better place.
- Mark, in the comments section, here:
http://www.luterra.com/blog/?p=1390

That is accurate only in hindsight.

Other public health issues like polio and AIDS have been addressed in a socially coherent manner

AIDS is somewhat like covid as it was politicized to a degree (Gay disease) and by parties that largely overlap those that politicized covid.

Track and trace and stop the outbreaks had to be tried and failed.

My hindsight says that covid was going to spread and that effort would fail.

But having a POTUS claim covid was a hoax was unconscionable.

Mark's comments in general looks to me that he has taken a similar "investigative" path as you and wrote a nice summary.

Posted: **Thu Feb 03, 2022 3:11 pm**

drstrangelove » Wed Feb 02, 2022 1:06 am wrote:
PufPuf93 » Tue Feb 01, 2022 11:48 pm wrote:The crisis we face as human is basic population ecology; we have too big a footprint on the planet. Population is fated to decline but as societies we have some choice in how population declines.
And this is the thing that gets me with the vaccines. Not the VAERS data or any other evidence for that matter.

Why would these people so very aware of this issue mandate the use of a vaccine that is a net benefit to population growth in the long run? Why not just develop a vaccine which doesn't work instead? Which appears to be closer to the truth. But if the vaccine just doesn't work, then why are they forcing everyone to take it at the cost of political stability?

With the amount of synthetic products we have later discovered cause cancer, it would be unsurprising if mRNA vaccines rapidly increase the speed at which cancer grows within the body. If you were going to do population culling with a vaccine, you wouldn't do it in such a way that everyone was dropping dead. You'd use a slow poison the effects of which gradually build over a number of years.

You have the virus circulating, culling the weak and fragile, who are marked as such by their weakened immune systems. But is this enough of a population reduction? If not, then you need a more dangerous virus, which isn't safe because you can't control it. But you can control the administration of the cure. Specifically in batches.

Could this be done? Yes.

Would the people running things actually do this? Yes.

Have they?

Thank you for this.

Humanity is disorganized and full of opportunists.

Most of us are confused over covid and getting increasingly frustrated and angry.

Probably everything has been considered and some are true.

Posted: **Thu Feb 03, 2022 3:23 pm**

PufPuf93 » Thu Feb 03, 2022 1:53 pm wrote:
Belligerent Savant » Tue Feb 01, 2022 9:33 pm wrote:.
Probably one of the most accurate and succinct takes on covid:

If only we could have seen the pandemic as something to be endured, survived, mitigated – rather than controlled or ended through our interventions – then we could have been in a much better place.
- Mark, in the comments section, here:
http://www.luterra.com/blog/?p=1390
That is accurate only in hindsight.

Other public health issues like polio and AIDS have been addressed in a socially coherent manner

AIDS is somewhat like covid as it was politicized to a degree (Gay disease) and by parties that largely overlap those that politicized covid.

Track and trace and stop the outbreaks had to be tried and failed.

My hindsight says that covid was going to spread and that effort would fail.

But having a POTUS claim covid was a hoax was unconscionable.

Mark's comments in general looks to me that he has taken a similar "investigative" path as you and wrote a nice summary.

EDIT, as it seems I misinterpreted some of your commentary.

Here's what I initially typed:

Sorry, Puf - this is a coronavirus, this is nothing like Polio. Polio vaccines are sterilizing. Covid "vaccines" clearly are NOT sterilizing (they also don't prevent spread/contagion and have FAR more reported side effects than the polio vaccine; indeed the side effect tally for these mRNA products far surpassed the AE tallies of all historical vaccines, and it accomplished this within a year of deployment). Covid also has animal reservoirs, and as a coronavirus, will NOT be "ended" with vaccines.

------

Additional comment, edited in after the initial post:

I'd add to the above that polio is a poor comparison to covid for the reasons outlined above. I'd further argue that covid, the 'pandemic' and all related govt/media messaging was all part of a multi-pronged agenda using a "public health issue" as cover to impose draconian subjugations and paradigm shifts in social orders/previously accepted 'norms' (as part of a 4th industrial revolution, in shorthand); If I understand your own comments here, I believe you seem to believe one of the agendas involve a depopulation program of some sort (ostensibly to offset natural resource depletion, etc.). Regardless, it's clear by now this crisis was implemented to achieve large-scale objectives, and the well-being of citizens, globally, was never a consideration, other than its use as a tool to impose fear and compliance.

--------

AIDS? Surely you jest. What was socially coherent about how AIDS was handled? You still trust Fauci much more than you should.

You offer no substance here other than broad stroke commentary (and even weaker attempts to criticize 'investigative paths') as if we're all still working with data points from May 2020.

It's now 2022.

We know far more know about what this virus is, and what it isn't, and also just how lethal it actually is -- even the "experts" that so many relied on back in 2020 have backpedaled on a number of prior proclamations Re: masks, lockdowns, social distancing, etc. What, precisely, have you offered here as far as substantive investigative reporting? What, precisely, is your position?

Time to dig a bit deeper. Or not, but please don't expect to be taken seriously here with drive-by commentary like your offering above.

----
Additional content added:

Also: you reference "hindsight" above. This is a misrepresentation. As this very thread demonstrates, a number of us here have been questioning and/or calling out the lies and potential for ulterior motive as far back as 2020, while many others at the time were still fully subscribing to many of the dominant narratives (in no small part because the narratives were supported by historically "liberal/leftist" institutions/publications).

YOU, and others, have fallen prey to these lies. Based on some recent commentary here over the last few days, it seems you continue to subscribe to some of the partisan tropes meant only to perpetuate division.

But having a POTUS claim covid was a hoax was unconscionable.

There have been many truly unconscionable acts perpetrated on The People since 2020. Trump calling covid a hoax is at the bottom of that list, if it exists on any list at all. This statement by Trump had zero lasting impact on subsequent developments, demonstrably, and only served to stoke the fury of the demographic he was targeting: those of your ilk.

He is an uber troll (a good one at that), and you -- along with so many others -- continue to be suffering from lingering effects of Trump Derangement Syndrome, in 2022, while so many more egregious crimes against humanity have been committed (none of which influenced by the words or actions of Orange Man Bad).

This is tragic, and borderline despicable at this point.

Posted: **Thu Feb 03, 2022 4:18 pm**

LOL that I can't do math because I try to cast a critical eye on totally cooked official statistics purporting to show the amazing benefits of shitty, leaky, experimental gene therapies that lose 95%+ of their efficacy in roughly 12 weeks and that appear to have negative efficacy against the transmission of omicron.

Every single statistic produced is already inherently skewed in the direction of these shitty, leaky vaccines. The numerator is always skewed toward vaccines because of the definition that you are not "officially vaccinated" until two weeks after you get each of these shots and boosters.

And the denominator is always overestimated for vaccinated populations because current and not historically accurate estimates are made for both the vaccinated and unvaccinated populations and because every locale has every reason to overestimate its own rate of vaccination in any case.

Finally, the unvaccinated population includes the most indigent, linguistically challenged, deathbed ridden, and hospital and doctor fearing individuals in any society. So of course we would expect some death associated with COVID-19 in this population anytime COVID-19 is prevalent. The fact that last week in NSW there were just 11 deaths associated with that entire population under 80 (compared to 64 fully vaccinated) simply cannot be presented as evidence of these vaccine's efficacy, even assuming that these vaccines were as harmless to people as the placebos they now appear to be in terms of their effectiveness.

Posted: **Thu Feb 03, 2022 6:40 pm**

.

@Humble_Analysis
·
Persons older than 50 account for 92% of all covid deaths in the USA and this group is 84% fully vaccinated.

This level of vaccination should, in theory, have reduced covid mortality by at least 78%. Including vaccinations of younger adults, covid death should be down 90%.

Overall, deaths are down ~50% versus last Winter... how much of this is due to mildness of Omicron or reduced vulnerable population (already infected in prior waves)?

Interestingly, deaths during Summer were higher this year, despite 80% vax rate.

https://twitter.com/Humble_Analysis/sta ... kWFdc8hyug

@cpcriser
·
Replying to
@Humble_Analysis

Yet in many locations around the world with even better vaccination rates than America they are seeing their highest amount of deaths. Even if you remove and extra 30% of deaths for “extra incidental” covid which is nonsense imo. You’re still talking a reduction of 20%.

And why shouldn’t there be a reduction anyways? Omicron is less lethal than it is transmissible. We have better therapeutics. Better mental. Less tinder and vulnerable. Etc etc etc. that 20% could literally zero to do with vax

https://twitter.com/cpcriser/status/148 ... kWFdc8hyug

Posted: **Thu Feb 03, 2022 6:57 pm**

stickdog99 » Thu Feb 03, 2022 8:18 pm wrote:And the denominator is always overestimated for vaccinated populations...

Sorry, Stickdog, but that's just not true!

When calculating the vaccine 'take-up' rate, the denominator is often underestimated.

Posted: **Thu Feb 03, 2022 7:33 pm**

alloneword » 03 Feb 2022 22:57 wrote:
stickdog99 » Thu Feb 03, 2022 8:18 pm wrote:And the denominator is always overestimated for vaccinated populations...
Sorry, Stickdog, but that's just not true!

When calculating the vaccine 'take-up' rate, the denominator is often underestimated.

The vaccinated population is consistently overestimated and the unvaccinated population is consistently underestimated in all officially sanctioned case, hospitalization, and mortality per 100,000 rate denominators.

Posted: **Thu Feb 03, 2022 7:59 pm**

.

Completely forgot about the below thread topic until alloneword linked it above. Good stuff. Cross-posting here:

alloneword » Thu Feb 03, 2022 9:54 am wrote:One thought that occurred regarding the source of the problem lies in the baseline stats used to calculate the number of 'unvaccinated'.

A curious thing in this data... if you total up all of the person-years across all ages and all vax status, adjust for it only being 10 months of data (so x ~1.2 to make it a year), you get a figure of 39,217,662 persons (or person-years over 1 year, to be exact).

The population of England (2020 mid year estimate) was 56,550,000... so where are the ~17 million missing people? They don't all appear to have died!

The ONS tell us that in 2020, 6,778,905 people were under 10 years old, so that leaves us with 49,771,233 over 10 yrs. That's still 10,553,571 people missing from our data.

The UKGov 'covid dashboard' informs us that (on 31/10/21 - when our dataset runs up to) 86.6% of the population of England were vaxxed with at least 1 dose.

If we work out the percentage (based on person years) of vaxxed in our data, we get a mere 59.61%. Odd.

It doesn't seem too unreasonable to assume that of these missing 10 million+ 'missing' people, most would be 'unvaxxed', since if they did take the shot, they'd be in the data, whereas if they didn't, they might well not be in the NIMS database at all.

So what happens if we simply throw these 10m into the 'unvaxxed' catagory?

We get a vax uptake figure of 47% for all those 'eligible' (over 10), which drops to 41% population wide.

OK, so what happens if we take those 10m people, then distribute them proportionally across the 'unvaxxed' age groups in our data?

This:

..and the ratio:

Which, to my eye, looks like the amazing magic healing properties of the vax on non-covid deaths have all but disappeared - only to be replaced by a much greater risk profile for younger people.

Now, here's my theory:

In an effort to inflate the vax uptake figures, they've been systematically suppressing the population denominator of the unvaxxed. This has had unintended consequences, as discussed, but nobody cares enough to worry about/notice it. That is all.

Posted: **Thu Feb 03, 2022 9:07 pm**

No deadly pandemic, no deadly virus, nothing but a giant murderous scam, ludicrously obvious since no later than the summer of 2020. Its success has been breathtaking. It depended solely on a thoroughly corrupted and systematically miseducated middle class pocketing its fee, following its cues obediently, and never going so far as to think the thinkable. (That way madness lies.)

In the context of no-context:

Don't ask for a big pay rise, warns Bank of England boss

By Szu Ping Chan
Business reporter, BBC News

Published 5 hours ago

Workers should not ask for big pay rises, to try and stop prices rising out of control, the Bank of England governor has told the BBC.

Prices are expected to climb faster than pay, putting the biggest squeeze on household finances in decades.

Andrew Bailey said the Bank raised rates to 0.5% from 0.25% to prevent rising prices becoming "ingrained".

Asked if the Bank was also implicitly asking workers not to demand big pay rises, he said: "Broadly, yes".

[...]

https://www.bbc.com/news/business-60206564

Nostradamus I ain't, but there is not one aspect of this global technofascist coup that I and countless others failed to predict in detail. It didn't require clairvoyance, nor was it rocket science.

FFS, not only were the perpetrators already notorious liars and leeches; they announced their plans in advance.

Posted: **Thu Feb 03, 2022 9:16 pm**

Groaniad Airhead Belatedly Starts Thinking Thoughts

(Weird how that column suddenly stops dead. Presumably she'd just fallen asleep over the bottle.)

Posted: **Thu Feb 03, 2022 10:07 pm**

@JeffWellsRigInt 9 hrs ago.

The genius of the bio-security state is its unrivaled amplification of insecurity. The threat now becomes your own genome. If you can be propagandized into supporting a War on Yourself you'll never be safe enough and can be terrorized and exploited endlessly.

https://twitter.com/JeffWellsRigInt/sta ... 4384925697

Posted: **Thu Feb 03, 2022 11:19 pm**

.
Good for Shaq. "Turner" is an utter fool, twisting knots in an attempt to claim a mandate is not "force".

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